Genomic transcriptional profiling of the developmental cycle of Chlamydia trachomatis.

  title={Genomic transcriptional profiling of the developmental cycle of Chlamydia trachomatis.},
  author={Robert J. Belland and Guangming Zhong and Deborah D. Crane and Daniel Hogan and Daniel E. Sturdevant and Jyotika Sharma and Wandy L. Beatty and Harlan D. Caldwell},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={100 14},
Chlamydia trachomatis is one of the most common bacterial pathogens and is the etiological agent of debilitating sexually transmitted and ocular diseases in humans. The organism is an obligate intracellular prokaryote characterized by a highly specialized biphasic developmental cycle. We have performed genomic transcriptional analysis of the chlamydial developmental cycle. This approach has led to the identification of a small subset of genes that control the primary (immediate-early genes) and… CONTINUE READING
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Chlamydia: Intracellular Biology, Pathogenesis, and Immunity

  • T. P. Hatch
  • 1999

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