Genomic structure of the spermatid-specific hsp70 homolog gene located in the class III region of the major histocompatibility complex of mouse and man.

@article{Ito1998GenomicSO,
  title={Genomic structure of the spermatid-specific hsp70 homolog gene located in the class III region of the major histocompatibility complex of mouse and man.},
  author={Yuji Ito and Akikazu Ando and Hitoshi Ando and Junko Ando and Yukio Saijoh and Hidetoshi Inoko and Hirokazu Fujimoto},
  journal={Journal of biochemistry},
  year={1998},
  volume={124 2},
  pages={347-53}
}
The Hsc70t gene is a Hsp70 homolog gene expressed constitutively in spermatids in mice. This gene is linked to two heat-inducible Hsp70 genes, Hsp70.1 and Hsp70.3, located in the MHC class III region. The syntenic region of human chromosome 6 contains the HSPA1B, HSPA1A, and HSPA1L genes. Here, we have isolated a HSPA1L cDNA clone from human testicular cells. The HSPA1L gene contained an intron 13 bp upstream of the initiating ATG. A similar genomic structure was found in the Hsc70t gene. The… CONTINUE READING
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