Genomic structure and promoter analysis of PKC-delta.

  title={Genomic structure and promoter analysis of PKC-delta.},
  author={K. Stephen Suh and Tamara T Tatunchak and John M Crutchley and Lindsay E Edwards and Keith G Marin and Stuart H. Yuspa},
  volume={82 1},
Protein kinase C-delta (PKC-delta) is a ubiquitously expressed kinase involved in a variety of cellular signaling pathways including cell growth, differentiation, apoptosis, tumor promotion, and carcinogenesis. While signaling pathways downstream of PKC-delta are well studied, the regulation of the gene has not been extensively analyzed. A mouse genomic DNA fragment containing the PKC-delta gene was sequenced by the primer-walking method, and the subsequent DNA sequence data were used as a… CONTINUE READING


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