Genomic structure, promoter analysis and expression of the porcine (Sus scrofa) TLR4 gene.

@article{Thomas2006GenomicSP,
  title={Genomic structure, promoter analysis and expression of the porcine (Sus scrofa) TLR4 gene.},
  author={Anne VT Thomas and Aurore D. Broers and H{\'e}l{\`e}ne F Vandegaart and Daniel J-M Desmecht},
  journal={Molecular immunology},
  year={2006},
  volume={43 6},
  pages={653-9}
}
Toll-like receptor 4 (TLR4) is essential for initiating the innate response to lipopolysaccharide (LPS) from Gram-negative bacteria by acting as a signal-transducing receptor. As the pig industry faces a unique array of related pathogens, it is anticipated that the genotype of swine TLR4 could be of crucial importance in future strategies aimed at improving genetic resistance to infectious diseases. In order to help in investigating TLR4 as a candidate disease-resistance gene in pigs, we… CONTINUE READING

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