Genomic signature and protein sequence analysis of a novel influenza A (H7N9) virus that causes an outbreak in humans in China.

@article{Liu2013GenomicSA,
  title={Genomic signature and protein sequence analysis of a novel influenza A (H7N9) virus that causes an outbreak in humans in China.},
  author={Qi Liu and Lu Lu and Zhiwu Sun and Guang-Wu Chen and Yumei Wen and Shibo Jiang},
  journal={Microbes and infection},
  year={2013},
  volume={15 6-7},
  pages={
          432-9
        }
}
Very recently, a new avian flu outbreak in humans, which is caused by a novel H7N9 influenza A virus (AIV), was reported in China. As of April 13, 2013, 49 confirmed cases (mainly middle-aged to elderly males), including 11 deaths, were reported in China. Here we analyzed the genomic signatures and protein sequences of the human H7N9 AIVs. We found that the genomic signatures of A(H7N9) had high and low identity to avian and human IAVs, respectively, suggesting its avian origin. The signature… CONTINUE READING
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