Genomic relationship between SINE retrotransposons, Pol III-Pol II transcription, and chromatin organization: the journey from junk to jewel.

@article{Lunyak2011GenomicRB,
  title={Genomic relationship between SINE retrotransposons, Pol III-Pol II transcription, and chromatin organization: the journey from junk to jewel.},
  author={Victoria V. Lunyak and Michelle B Atallah},
  journal={Biochemistry and cell biology = Biochimie et biologie cellulaire},
  year={2011},
  volume={89 5},
  pages={495-504}
}
A typical eukaryotic genome harbors a rich variety of repetitive elements. The most abundant are retrotransposons, mobile retroelements that utilize reverse transcriptase and an RNA intermediate to relocate to a new location within the cellular genomes. A vast majority of the repetitive mammalian genome content has originated from the retrotransposition of SINE (100-300 bp short interspersed nuclear elements that are derived from the structural 7SL RNA or tRNA), LINE (7kb long interspersed… CONTINUE READING

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