Genomic profiling of circulating plasma RNA for the analysis of cancer.

@article{Collado2007GenomicPO,
  title={Genomic profiling of circulating plasma RNA for the analysis of cancer.},
  author={Manuel Collado and V. Vallina Garc{\'i}a and Jos{\'e} Miguel Garc{\'i}a and Isabel Alonso and Luis J. Lombard{\'i}a and Ram{\'o}n D{\'i}az-Uriarte and Luis L{\'o}pez Fern{\'a}ndez and {\'A}ngel Zaballos and F{\'e}lix Bonilla and Manuel Serrano},
  journal={Clinical chemistry},
  year={2007},
  volume={53 10},
  pages={1860-3}
}
BACKGROUND The blood of cancer patients is known to contain fragments of RNA released from the tumor. The application of genomic profiling techniques to plasma RNA may allow the unbiased selection of cancer markers in the blood, but the informative value of genomic profiling of plasma RNA is currently unknown. METHODS We used cDNA microarray hybridization to perform genomic profiling of plasma RNA from colorectal cancer (CRC) patients and from healthy donors. From a list of 40 genes… CONTINUE READING