Genomic profiling associated with recurrence in patients with rectal cancer treated with chemoradiation.

@article{Gordon2006GenomicPA,
  title={Genomic profiling associated with recurrence in patients with rectal cancer treated with chemoradiation.},
  author={Michael A. Gordon and Ji Gil and Bo Lu and Wu Zhang and Dongyun Yang and Jim Yun and Sylke Schneider and Susan Groshen and Syma Iqbal and Oliver A. Press and Katrin E Rhodes and H. P. Lenz},
  journal={Pharmacogenomics},
  year={2006},
  volume={7 1},
  pages={67-88}
}
PURPOSE Stage II and III adenocarcinoma of the rectum has an overall 5-year survival rate of approximately 50%, and tumor recurrence remains a major problem despite an improvement in local control through chemotherapy and radiation. The efficacy of chemoradiation therapy may be significantly compromised as a result of interindividual variations in clinical response and host toxicity. Therefore, it is imperative to identify those patients who will benefit from chemoradiation therapy and those… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

Similar Papers

Loading similar papers…