Genomic prediction of cognitive traits in childhood and adolescence

@article{Allegrini2019GenomicPO,
  title={Genomic prediction of cognitive traits in childhood and adolescence},
  author={A G Allegrini and Saskia Selzam and Kaili Rimfeld and Sophie von Stumm and Jean-Baptiste Pingault and Robert Plomin},
  journal={Molecular Psychiatry},
  year={2019},
  volume={24},
  pages={819-827}
}
Recent advances in genomics are producing powerful DNA predictors of complex traits, especially cognitive abilities. Here, we leveraged summary statistics from the most recent genome-wide association studies of intelligence and educational attainment, with highly genetically correlated traits, to build prediction models of general cognitive ability and educational achievement. To this end, we compared the performances of multi-trait genomic and polygenic scoring methods. In a representative UK… CONTINUE READING

Figures and Topics from this paper.

References

Publications referenced by this paper.
SHOWING 1-10 OF 41 REFERENCES

Predicting educational achievement from DNA.

  • Molecular psychiatry
  • 2017
VIEW 3 EXCERPTS

Blueprint: how DNA makes us who we are

R. Plomin
  • 2018
VIEW 1 EXCERPT

Genetic analysis of social-class mobility in five longitudinal studies

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2018
VIEW 1 EXCERPT