Genomic organization of the mouse pore-forming protein (perforin) gene and localization to chromosome 10. Similarities to and differences from C9

@article{Trapani1990GenomicOO,
  title={Genomic organization of the mouse pore-forming protein (perforin) gene and localization to chromosome 10. Similarities to and differences from C9},
  author={Joseph A. Trapani and Byoung S. Kwon and Christine A. Kozak and Chaya Chintamaneni and J. Young and B J Dupont},
  journal={The Journal of Experimental Medicine},
  year={1990},
  volume={171},
  pages={545 - 557}
}
Genomic clones encompassing the entire coding region of the mouse lymphocyte pore-forming protein gene (Pfp) have been isolated and used to determine its intron-exon organization. In contrast to C9, Pfp has a simple structure, consisting of only three exons (two of which encode polypeptide), a large 5' intron, and a single, smaller intron that is situated… CONTINUE READING