Genomic organization of the immunoglobulin light chain gene loci in Xenopus tropicalis: evolutionary implications.

@article{Qin2008GenomicOO,
  title={Genomic organization of the immunoglobulin light chain gene loci in Xenopus tropicalis: evolutionary implications.},
  author={Tong Qin and Liming Ren and Xiao Xiang Hu and Ying Guo and Jing Fei and Qinghong Zhu and John E. Butler and Changxin Wu and Ning Li and Lennart Hammarstrom and Yaofeng Zhao},
  journal={Developmental and comparative immunology},
  year={2008},
  volume={32 2},
  pages={156-65}
}
Based on presently available genome data, we characterized the genomic organization of all three light chain gene (rho, sigma and type III) loci in Xenopus tropicalis. The rho gene locus in X. tropicalis, structurally similar to the kappa gene loci in mammals, was shown to contain a single C rho gene and nine J rho segments. The sigma locus also contains a single C gene, although two distinct C sigma genes have previously been found in Xenopus laevis (most likely due to chromosome polyploidy… CONTINUE READING

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