Genomic organization of the crested ibis MHC provides new insight into ancestral avian MHC structure

@inproceedings{Chen2015GenomicOO,
  title={Genomic organization of the crested ibis MHC provides new insight into ancestral avian MHC structure},
  author={Li-Cheng Chen and Hong Lan and Li Ye Sun and Yan-Li Deng and Ke-Yi Tang and Q. H. Wan},
  booktitle={Scientific reports},
  year={2015}
}
The major histocompatibility complex (MHC) plays an important role in immune response. Avian MHCs are not well characterized, only reporting highly compact Galliformes MHCs and extensively fragmented zebra finch MHC. We report the first genomic structure of an endangered Pelecaniformes (crested ibis) MHC containing 54 genes in three regions spanning ~500 kb. In contrast to the loose BG (26 loci within 265 kb) and Class I (11 within 150) genomic structures, the Core Region is condensed (17… CONTINUE READING
BETA

References

Publications referenced by this paper.
SHOWING 1-10 OF 62 REFERENCES

Natural history of the major histocompatibility complex. 1–775

J. Klein
  • 1986
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Nipponia nippon. The IUCN Red List of Threatened Species (2014) Avaiable at: www.iucnredlist.org (Accessed: 28/01/2014)

BirdLife International
  • 2014

Genome analysis and signature discovery for diving and sensory properties of the endangered Chinese alligator

Wan, H Q.
  • Cell Res
  • 2013

Characterization of the MHC class II a-chain gene in ducks

Ren, M L.
  • Immunogenetics 63,
  • 2011

Characterization of the MHC class II a-chain gene in ducks

Ren, M L.
  • Immunogenetics 63,
  • 2011

Similar Papers