Genomic organization of alpha satellite DNA on human chromosome 7: evidence for two distinct alphoid domains on a single chromosome.

@article{Waye1987GenomicOO,
  title={Genomic organization of alpha satellite DNA on human chromosome 7: evidence for two distinct alphoid domains on a single chromosome.},
  author={John S. Waye and Sarah Beatrice England and Huntington F. Willard},
  journal={Molecular and cellular biology},
  year={1987},
  volume={7 1},
  pages={
          349-56
        }
}
A complete understanding of chromosomal disjunction during mitosis and meiosis in complex genomes such as the human genome awaits detailed characterization of both the molecular structure and genetic behavior of the centromeric regions of chromosomes. Such analyses in turn require knowledge of the organization and nature of DNA sequences associated with centromeres. The most prominent class of centromeric DNA sequences in the human genome is the alpha satellite family of tandemly repeated DNA… CONTINUE READING

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