Genomic organization and tissue expression of mouse proteasome gene Lmp-2.

@article{Zhou1993GenomicOA,
  title={Genomic organization and tissue expression of mouse proteasome gene Lmp-2.},
  author={Paul Zhou and E Zanelli and Michele Smart and Chantal David},
  journal={Genomics},
  year={1993},
  volume={16 3},
  pages={664-8}
}
The mouse Lmp-2 gene is located within the major histocompatibility complex (MHC) class II region and encodes a subunit of the 20S cytosolic proteasome. Previous studies indicated that the 20S proteasome is a catalytic core of the 26S proteolytic complex that possesses a latent multicatalytic proteinase activity and catalyzes an ATP-dependent, selective breakdown of proteins ligated to ubiquitin. This complex has recently been postulated to be involved in the processing of endogenous antigenic… CONTINUE READING
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