Genomic organization and promoter characterization of human CXCR4 gene 1

@article{Caruz1998GenomicOA,
  title={Genomic organization and promoter characterization of human CXCR4 gene
 
1},
  author={Antonio Caruz and Maikel Samsom and Jos{\'e} Mar{\'i}a Alonso and Jos{\'e} Alcam{\'i} and Françoise Baleux and Jean Louis Virelizier and Marc Parmentier and Fernando Arenzana‐Seisdedos},
  journal={FEBS Letters},
  year={1998},
  volume={426}
}
Cutting edge: CXCR4-Lo: molecular cloning and functional expression of a novel human CXCR4 splice variant.
TLDR
Exposure to rat basophil leukemia-2H3 cells responded to SDF-1 with a transient rise of intracellular Ca2+ concentration and by undergoing chemotaxis, indicating differential affinity as a coreceptor for HIV strains in comparison with CXCR4.
Short Communication HTLV Type I Tax Activation of the CXCR4 Promoter by Association with Nuclear Respiratory Factor 1
TLDR
It is demonstrated that Tax trans -activates the promoter for CXCR4, a coreceptor for T cell-tropic HIV-1 through its association with nuclear respiratory factor 1 (NRF1), which contains an NRF1-binding site, crucial for basal and Tax-induced activity.
CD30 triggering by agonistic antibodies regulates CXCR4 expression and CXCL12 chemotactic activity in the cell line L540.
TLDR
It is demonstrated here, in the Hodgkin-derived L540 cell line, that CD30 regulates the prototypic lymphoid chemokine receptor CXCR4 (CD184), which plays an important role in many organ systems and is a coreceptor for human immunodeficiency virus-1 entry.
The Role of CXCR7/RDC1 as a Chemokine Receptor for CXCL12/SDF-1 in Prostate Cancer*
TLDR
A role for CXCR7/RDC1 in PCa metastasis and progression is demonstrated and potential targets for therapeutic intervention are suggested.
Chemokine receptor trio: CXCR3, CXCR4 and CXCR7 crosstalk via CXCL11 and CXCL12.
The Chemokine Receptor CXCR4 is Regulated by DNA Methylation in Pancreatic Cancer
TLDR
It is demonstrated that DNAmethylation influences CXCR4 expression in human pancreatic cancer, the first evidence for epigenetic regulation of CX CR4 in human cancers, providing new insights into the role of C XCR4/CXCL12 interactions in tumor progression.
CXCL12 / CXCR4 / CXCR7 chemokine axis and cancer progression
TLDR
The current concepts regarding the role of CXCL12 / CXCR4 / CxCR7 axis activation, which regulates the pattern of tumor growth and metastatic spread to organs expressing high levels of CxCL12 to develop secondary tumors are reviewed.
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TLDR
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    Proceedings of the National Academy of Sciences of the United States of America
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TLDR
Linker scanning mutagenesis of this minimal promoter has established that both the previously identified octamer motif and a DNA motif that binds an unknown protein factor are critical for B29 gene expression in a pre-B-cell and B-cell line.
The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry
TLDR
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