Genomic organization, sequence, and chromosomal localization of the human helix-loop-helix Id1 gene.

@article{Nehlin1997GenomicOS,
  title={Genomic organization, sequence, and chromosomal localization of the human helix-loop-helix Id1 gene.},
  author={Jan O Nehlin and Eiji Hara and Wen Lin Kuo and Colin Collins and Judith Campisi},
  journal={Biochemical and biophysical research communications},
  year={1997},
  volume={231 3},
  pages={628-34}
}
The helix-loop-helix protein Id-1 regulates growth and differentiation in many mammalian cells. In human fibroblasts, Id1 and Id1', a putative splicing variant, are cell cycle regulated, essential for proliferation, repressed by senescence, and overexpressed by some tumor cells. To better understand Id1, we determined the complete sequence, transcriptional start, and localization of the human Id1 gene. Human Id1 has two exons (426 bp and 42 bp), separated by an intron (239 bp). Id1' results… CONTINUE READING

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