Genomic organization, complex splicing pattern and expression of a human septin gene on chromosome 17q25.3


The Ov/Br septin gene, which is also a fusion partner of MLL in acute myeloid leukaemia, is a member of a family of novel GTP binding proteins that have been implicated in cytokinesis and exocytosis. In this study, we describe the genomic and transcriptional organization of this gene, detailing seventeen exons distributed over 240 kb of sequence. Extensive… (More)
DOI: 10.1038/sj.onc.1204752


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