Genomic organisation and alternative splicing of mouse and human thioredoxin reductase 1 genes

@article{Osborne2001GenomicOA,
  title={Genomic organisation and alternative splicing of mouse and human thioredoxin reductase 1 genes},
  author={Simone A. Osborne and Kathryn F Tonissen},
  journal={BMC Genomics},
  year={2001},
  volume={2},
  pages={10 - 10}
}
Thioredoxin reductase (TR) is a redox active protein involved in many cellular processes as part of the thioredoxin system. Presently there are three recognised forms of mammalian thioredoxin reductase designated as TR1, TR3 and TGR, that represent the cytosolic, mitochondrial and novel forms respectively. In this study we elucidated the genomic organisation of the mouse (Txnrd1) and human thioredoxin reductase 1 genes (TXNRD1) through library screening, restriction mapping and database mining… CONTINUE READING

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