Genomic landscape of lymphoepithelioma‐like hepatocellular carcinoma

@article{Chan2019GenomicLO,
  title={Genomic landscape of lymphoepithelioma‐like hepatocellular carcinoma},
  author={A. Chan and Zhe Zhang and C. Chong and E. K. Tin and C. Chow and N. Wong},
  journal={The Journal of Pathology},
  year={2019},
  volume={249}
}
Lymphoepithelioma‐like hepatocellular carcinoma (LEL‐HCC) is a distinct variant of HCC that is characterized by dense tumor‐infiltrating lymphocytes (TILs). Patients with LEL‐HCC also show better clinical outcomes compared to conventional HCC (c‐HCC), which is commonly presented with low TIL. Emerging evidence has begun to highlight tumor‐intrinsic genetic abnormalities in the tumor–host immune interfaces. However, genome‐wide characterization of LEL‐HCC remains largely unexplored. Here, we… Expand
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