Genomic instability: Building bridges

Abstract

to induce genomic instability through a breakage–fusion–bridge cycle. Marzec et al. have described a different telomere-dependent mechanism by which genomic instability can be induced in cancer cells that use alternative lengthening of telomeres (ALT) for telomere maintenance. Previous data indicated that nuclear hormone receptor transcription factors of… (More)
DOI: 10.1038/nrc3933

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