Genomic insights into the Ixodes scapularis tick vector of Lyme disease

  title={Genomic insights into the Ixodes scapularis tick vector of Lyme disease},
  author={Monika Gulia-Nuss and Andrew Bradley Nuss and Jason M. Meyer and Daniel E. Sonenshine and Robert M. Roe and Robert M. Waterhouse and David B Sattelle and Jos{\'e} de la Fuente and Jos{\'e} M C Ribeiro and Karine Megy and Jyothi Thimmapuram and Jason R. Miller and Brian P. Walenz and Sergey Koren and Jessica B. Hostetler and Mathangi Thiagarajan and Vinita S. Joardar and Linda I. Hannick and Shelby L. Bidwell and Martin Hammond and Sarah K. Young and Qiandong Zeng and Jenica L. Abrudan and Francisca Cunha Almeida and Nieves Ayll{\'o}n and Ketaki P. Bhide and Brooke W. Bissinger and Elena Bonzon-Kulichenko and Steven Buckingham and Daniel R. Caffrey and Melissa Jo Caimano and Vincent Croset and Timothy W. Driscoll and Don Gilbert and Joseph J. Gillespie and Gloria I. Giraldo-Calder{\'o}n and Jeffrey M Grabowski and D. D. Jiang and Sayed Mohammed Khalil and Donghun Kim and Katherine M. Kocan and Juraj Ko{\vc}i and Richard J Kuhn and Timothy J. Kurtti and Kristin Lees and Emma G. Lang and Ryan C. Kennedy and Hyeogsun Kwon and Rushika Perera and Yumin Qi and Justin D. Radolf and Joyce M. Sakamoto and Alejandro S{\'a}nchez-Gracia and Maiara Santos Severo and Neal Silverman and Ladislav {\vS}imo and Marta Tojo and Cristian Tornador and Janice P. Van Zee and Jes{\'u}s V{\'a}zquez and Filipe G. Vieira and Margarita Antonia Luis Villar and Adam R. Wespiser and Yunlong Yang and Jiwei Zhu and Peter Arensburger and Patricia V Pietrantonio and Stephen C. Barker and Renfu Shao and Evgeny M. Zdobnov and Frank Hauser and Cornelis J P Grimmelikhuijzen and Yoonseong Park and Julio Rozas and Richard Benton and Jo{\~a}o H. F. Pedra and David R. Nelson and Maria F. Unger and Jos{\'e} M. C. Tub{\'i}o and Zhijian Tu and Hugh M. Robertson and Martin Shumway and Granger G. Sutton and Jennifer R. Wortman and Daniel Lawson and Stephen K. Wikel and Vishvanath M. Nene and Claire M. Fraser and Frank H. Collins and Bruce W. Birren and Karen E. Nelson and Elisabet Caler and Catherine A. Hill},
  booktitle={Nature communications},
Ticks transmit more pathogens to humans and animals than any other arthropod. We describe the 2.1 Gbp nuclear genome of the tick, Ixodes scapularis (Say), which vectors pathogens that cause Lyme disease, human granulocytic anaplasmosis, babesiosis and other diseases. The large genome reflects accumulation of repetitive DNA, new lineages of retro-transposons, and gene architecture patterns resembling ancient metazoans rather than pancrustaceans. Annotation of scaffolds representing ∼57% of the… CONTINUE READING


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Publications referenced by this paper.

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Hormonal regulation of metamorphosis and reproduction in ticks

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