Genomic imprinting on the X chromosome: implications for brain and behavioral phenotypes.

  title={Genomic imprinting on the X chromosome: implications for brain and behavioral phenotypes.},
  author={William Davies},
  journal={Annals of the New York Academy of Sciences},
  volume={1204 Suppl},
Imprinted genes, in contrast to most mammalian genes, are monoallelically expressed in a parent-of-origin dependent manner. The idiosyncratic expression profile associated with imprinted genes arises from the differential epigenetic marking of the alleles in the paternal and maternal germlines. Although small in number, imprinted genes can profoundly influence key developmental and physiological processes, including those in the brain; work in animal models and in humans has shown that such… CONTINUE READING


Publications citing this paper.
Showing 1-9 of 9 extracted citations

Biological factors underlying sex differences in neurological disorders.

The international journal of biochemistry & cell biology • 2015
View 2 Excerpts
Highly Influenced

Genomic imprinting effects of the X chromosome on brain morphology.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2013
View 4 Excerpts
Highly Influenced

Behavioral epigenetics.

Annals of the New York Academy of Sciences • 2011


Publications referenced by this paper.
Showing 1-10 of 45 references


Willison, K. 1991. Opposite imprinting of the mouse Igf2, 7 Igf2rgenes.TrendsGenet
E18 Ann. N.Y. Acad. Sci. 1204 • 2010

a new homeobox gene cluster

J. A. Maclean, 2nd et al. 2005. Rhox
Cell 120: 369–382. Ann. N.Y. Acad. Sci. 1204 • 2010

Comparison of gene expression in male and female mouse blastocysts revealed imprinting of the X - linked gene , Rhox 5 / Pem , at preimplantation stages

S. Kobayashi
Curr . Biol . • 2006

Similar Papers

Loading similar papers…