Genomic expression profiling in lymph nodes with lymphoid depletion from porcine circovirus 2-infected pigs.

@article{Lee2010GenomicEP,
  title={Genomic expression profiling in lymph nodes with lymphoid depletion from porcine circovirus 2-infected pigs.},
  author={Garam Lee and Dongun Han and Jae-Young Song and Yong-soon Lee and Kyung-sun Kang and Sorah Yoon},
  journal={The Journal of general virology},
  year={2010},
  volume={91 Pt 10},
  pages={
          2585-91
        }
}
Porcine circovirus type 2 (PCV2) is the main causative agent of porcine circovirus-associated disease, such as post-weaning multisystemic wasting syndrome, which involves lymphocyte depletion. However, little is known about the molecular mechanisms of lymphoid depletion. To gain insight into the interaction between virus and host cells, microarrays were used to analyse changes in genomic expression in lymph nodes following PCV2 infection of pigs, together with negative controls. Total RNA was… CONTINUE READING

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