Genomic evolution and complexity of the Anaphase-promoting Complex (APC) in land plants

  title={Genomic evolution and complexity of the Anaphase-promoting Complex (APC) in land plants},
  author={Marcelo de Freitas Lima and Nubia B Eloy and Camila Pegoraro and Rauan Sagit and Cristian A Rojas and Thiago Bretz and L{\'i}via Vargas and Arne Elofsson and Antonio Costa de Oliveira and Adriana Silva Hemerly and Paulo Cavalcanti Gomes Ferreira},
  booktitle={BMC Plant Biology},
The orderly progression through mitosis is regulated by the Anaphase-Promoting Complex (APC), a large multiprotein E3 ubiquitin ligase that targets key cell-cycle regulators for destruction by the 26 S proteasome. The APC is composed of at least 11 subunits and associates with additional regulatory activators during mitosis and interphase cycles. Despite extensive research on APC and activator functions in the cell cycle, only a few components have been functionally characterized in plants… CONTINUE READING
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and organization

  • L Cui, PK Wall, JH Leebens-Mack, BG Lindsay, DE Soltis, JJ Doyle
  • 2009

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