Genomic correlates of atherosclerosis in ancient humans.

  title={Genomic correlates of atherosclerosis in ancient humans.},
  author={Albert Zink and L. Samuel Wann and R Christopher Thompson and Andreas Keller and Frank Maixner and Adel Hassan Allam and Caleb E. Finch and Bruno Frohlich and Hillard S. Kaplan and Guido P Lombardi and M. Linda Sutherland and James D Sutherland and Lucia Watson and Samantha L. Cox and Michael I. Miyamoto and Jagat P Narula and Alexandre F. R. Stewart and Gregory S. Thomas and Johannes Krause},
  journal={Global heart},
  volume={9 2},
Paleogenetics offers a unique opportunity to study human evolution, population dynamics, and disease evolution in situ. Although histologic and computed x-ray tomographic investigations of ancient mummies have clearly shown that atherosclerosis has been present in humans for more than 5,000 years, limited data are available on the presence of genetic predisposition for cardiovascular disease in ancient human populations. In a previous whole-genome study of the Tyrolean Iceman, a 5,300-year-old… CONTINUE READING
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Why did ancient people have atherosclerosis? From autopsies to computed tomography to potential risk factors

  • GS Thomas, LS Wann, AH Allam
  • Glob Heart 2014;9:229–37
  • 2014

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