Genomic control, a new approach to genetic-based association studies.

@article{Devlin2001GenomicCA,
  title={Genomic control, a new approach to genetic-based association studies.},
  author={Bernie J Devlin and Kathryn Roeder and Larry A. Wasserman},
  journal={Theoretical population biology},
  year={2001},
  volume={60 3},
  pages={155-66}
}
During the past decade, mutations affecting liability to human disease have been discovered at a phenomenal rate, and that rate is increasing. For the most part, however, those diseases have a relatively simple genetic basis. For diseases with a complex genetic and environmental basis, new approaches are needed to pave the way for more rapid discovery of genes affecting liability. One such approach exploits large, population-based samples and large-scale genotyping to evaluate disease/gene… CONTINUE READING
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