Genomic control, a new approach to genetic-based association studies.

@article{Devlin2001GenomicCA,
  title={Genomic control, a new approach to genetic-based association studies.},
  author={Bernie Devlin and Kathryn Roeder and Larry A. Wasserman},
  journal={Theoretical population biology},
  year={2001},
  volume={60 3},
  pages={
          155-66
        }
}
During the past decade, mutations affecting liability to human disease have been discovered at a phenomenal rate, and that rate is increasing. For the most part, however, those diseases have a relatively simple genetic basis. For diseases with a complex genetic and environmental basis, new approaches are needed to pave the way for more rapid discovery of genes affecting liability. One such approach exploits large, population-based samples and large-scale genotyping to evaluate disease/gene… 

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...

References

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TLDR
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This report generalizes genomic control to quantitative traits (QT) and multilocus models, and shows that GC controls spurious associations in reasonable settings of population substructure for QT models, including gene‐gene interaction.

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TLDR
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