Genomic cloning, structure, expression pattern, and chromosomal location of the human SIX3 gene.

@article{Granadino1999GenomicCS,
  title={Genomic cloning, structure, expression pattern, and chromosomal location of the human SIX3 gene.},
  author={Bego{\~n}a Granadino and Mar{\'i}a Esther Gallardo and Javier L{\'o}pez-R{\'i}os and Raul Sanz and Cynthia Ramos and Carmen Ayuso and Paola Bovolenta and Santiago Rodr{\'i}guez de C{\'o}rdoba},
  journal={Genomics},
  year={1999},
  volume={55 1},
  pages={100-5}
}
The Drosophila gene sine oculis (so) is a nuclear homeoprotein that is required for eye development. Homologous genes to so, denoted SIX genes, have been found in vertebrates. Among the SIX genes, SIX3 is considered to be the functional homologue of so. To provide insight into the potential implications of SIX3 in human ocular malformations, we have cloned and characterized the human SIX3 gene. In human eye, SIX3 produces a 3-kb transcript that codes for a 332-amino-acid polypeptide that is… CONTINUE READING
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