Genomic characterization of the human heterotrimeric G protein alpha, beta, and gamma subunit genes.

@article{Hurowitz2000GenomicCO,
  title={Genomic characterization of the human heterotrimeric G protein alpha, beta, and gamma subunit genes.},
  author={E H Hurowitz and J. M. Melnyk and Y. J. Chen and Hosein Kouros-Mehr and Melvin I. Simon and Hiroaki Shizuya},
  journal={DNA research : an international journal for rapid publication of reports on genes and genomes},
  year={2000},
  volume={7 2},
  pages={111-20}
}
Heterotrimeric guanine nucleotide binding proteins (G proteins) transduce extracellular signals received by transmembrane receptors to effector proteins. Each subunit of the G protein complex is encoded by a member of one of three corresponding gene families. Currently, 16 different members of the alpha subunit family, 5 different members of the beta subunit family, and 11 different members of the gamma subunit family have been described in mammals. Here we have identified and characterized… CONTINUE READING

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