Genomic characterization and sequence diversity of the β2-microglobulin gene in the miiuy croaker, Miichthys miiuy.

  title={Genomic characterization and sequence diversity of the $\beta$2-microglobulin gene in the miiuy croaker, Miichthys miiuy.},
  author={Y N Sun and Xiurong Su and Tianjun Xu and T W Li},
  journal={Genetics and molecular research : GMR},
  volume={14 3},
β2-Microglobulin (β2m) is related to major histocompatibility complex class I alpha chains, and forms cell-surface glycoproteins that mediate a variety of functions in immune defense. In general, β2m has no isoforms and is not polymorphic in higher vertebrates, but polymorphisms between different alleles have been found in some fish species. In this study, full-length β2m cDNA and genomic sequences were cloned from the miiuy croaker (Miichthys miiuy). The miiuy croaker β2m gene shares many of… 

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  • B. ShumK. Azumi P. Parham
  • Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 1996
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