Genomic changes following host restriction in bacteria.

@article{Moran2004GenomicCF,
  title={Genomic changes following host restriction in bacteria.},
  author={Nancy A Moran and Gordon R Plague},
  journal={Current opinion in genetics & development},
  year={2004},
  volume={14 6},
  pages={627-33}
}
Many genomic sequences have been recently published for bacteria that can replicate only within eukaryotic hosts. Comparisons of genomic features with those of closely related bacteria retaining free-living stages indicate that rapid evolutionary change often occurs immediately after host restriction. Typical changes include a large increase in the frequency of mobile elements in the genome, chromosomal rearrangements mediated by recombination among these elements, pseudogene formation, and… CONTINUE READING

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Insertion sequences revisited

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Highly Influential
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