Genomic association of the proteasome demonstrates overlapping gene regulatory activity with transcription factor substrates.

Abstract

The proteasome can regulate transcription through proteolytic processing of transcription factors and via gene locus binding, but few targets of proteasomal regulation have been identified. Using genome-wide location analysis and transcriptional profiling in Saccharomyces cerevisiae, we have established which genes are bound and regulated by the proteasome… (More)

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@article{Auld2006GenomicAO, title={Genomic association of the proteasome demonstrates overlapping gene regulatory activity with transcription factor substrates.}, author={Kathryn L Auld and Christopher R. Brown and Jason M. Casolari and Suzanne Komili and Pamela A. Silver}, journal={Molecular cell}, year={2006}, volume={21 6}, pages={861-71} }