Genomic and proteomic characterization of the broad-host-range Salmonella phage PVP-SE1: creation of a new phage genus.

@article{Santos2011GenomicAP,
  title={Genomic and proteomic characterization of the broad-host-range Salmonella phage PVP-SE1: creation of a new phage genus.},
  author={Silvio B Santos and Andrew M Kropinski and P J Ceyssens and H. W. Ackermann and Andre Villegas and Rob Lavigne and Victor N. Krylov and Carla M. Carvalho and Eug{\'e}nio C. Ferreira and Joana Azeredo},
  journal={Journal of virology},
  year={2011},
  volume={85 21},
  pages={11265-73}
}
(Bacterio)phage PVP-SE1, isolated from a German wastewater plant, presents a high potential value as a biocontrol agent and as a diagnostic tool, even compared to the well-studied typing phage Felix 01, due to its broad lytic spectrum against different Salmonella strains. Sequence analysis of its genome (145,964 bp) shows it to be terminally redundant and circularly permuted. Its G+C content, 45.6 mol%, is lower than that of its hosts (50 to 54 mol%). We found a total of 244 open reading frames… CONTINUE READING
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