Genomic and genetic alterations influence the progression of gastric cancer.

@article{Nobili2011GenomicAG,
  title={Genomic and genetic alterations influence the progression of gastric cancer.},
  author={Stefania Nobili and Lorenzo Bruno and Ida Landini and Cristina Napoli and Paolo Bechi and Francesco Tonelli and Carlos A Rubio and Enrico Mini and Gabriella Nesi},
  journal={World journal of gastroenterology},
  year={2011},
  volume={17 3},
  pages={
          290-9
        }
}
Gastric cancer is one of the leading causes of cancer-related deaths worldwide, although the incidence has gradually decreased in many Western countries. Two main gastric cancer histotypes, intestinal and diffuse, are recognised. Although most of the described genetic alterations have been observed in both types, different genetic pathways have been hypothesized. Genetic and epigenetic events, including 1q loss of heterozygosity (LOH), microsatellite instability and hypermethylation, have… CONTINUE READING
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Detection and clinical significance of DNA repair gene ERCC8 tag SNPs in gastric cancer.

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