Genomic and biochemical insights into the specificity of ETS transcription factors.

@article{Hollenhorst2011GenomicAB,
  title={Genomic and biochemical insights into the specificity of ETS transcription factors.},
  author={Peter C. Hollenhorst and Lawrence P. McIntosh and Barbara J. Graves},
  journal={Annual review of biochemistry},
  year={2011},
  volume={80},
  pages={437-71}
}
ETS proteins are a group of evolutionarily related, DNA-binding transcriptional factors. These proteins direct gene expression in diverse normal and disease states by binding to specific promoters and enhancers and facilitating assembly of other components of the transcriptional machinery. The highly conserved DNA-binding ETS domain defines the family and… CONTINUE READING