Genomic analysis of drug resistant small cell lung cancer cell lines by combining mRNA and miRNA expression profiling

Abstract

Etoposide (VP16) combined with cisplatin (DDP), as the first-line chemotherapy for small cell lung cancer (SCLC), regularly confers drug resistance. The present study applied complementary (c)DNA and micro (mi)RNA microarray to identify gene and miRNA expression profiles associated with multidrug resistance (MDR) in SCLC. The VP16/DDP (VP16 combined with… (More)
DOI: 10.3892/ol.2017.5967

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