Genomic analysis of Ovis aries (Ovar) MHC class IIa loci

  title={Genomic analysis of Ovis aries (Ovar) MHC class IIa loci},
  author={Lynn M. Herrmann-Hoesing and Stephen N White and Lowell S. Kappmeyer and David R. Herndon and Donald P. Knowles},
Determining the genomic organization of the Ovis aries (Ovar) major histocompatibility complex class IIa region is essential for future functional studies related to antigen presentation. In this study, a bacterial artificial chromosome (BAC) library of genomic DNA from peripheral blood leukocytes (PBL) of a Rambouillet ram was constructed, and BAC clone consisting of the major histocompatibility complex (MHC) class II DQB2, DQA2, DQB1, DQA1, and DRB1 loci was identified and completely… CONTINUE READING