Genomic analysis and selected molecular pathways in rare cancers.

  title={Genomic analysis and selected molecular pathways in rare cancers.},
  author={Stephen V Liu and Elizabeth Lenkiewicz and Lisa Evers and Tara K. Holley and J. Kiefer and Christian Ruiz and Katharina Glatz and Lukas Bubendorf and Michael J. Demeure and Cathy Eng and Ramesh K. Ramanathan and Daniel D. Von Hoff and Michael T. Barrett},
  journal={Physical biology},
  volume={9 6},
It is widely accepted that many cancers arise as a result of an acquired genomic instability and the subsequent evolution of tumor cells with variable patterns of selected and background aberrations. The presence and behaviors of distinct neoplastic cell populations within a patient's tumor may underlie multiple clinical phenotypes in cancers. A goal of many current cancer genome studies is the identification of recurring selected driver events that can be advanced for the development of… CONTINUE READING


Publications citing this paper.


Publications referenced by this paper.

The landscape of cancer genes and mutational processes in breast cancer

  • P JStephens
  • Nature
  • 2012

The life history of 21 breast cancers

  • S Nik-Zainal
  • Cell
  • 2012

Disruption of the histone acetyltransferase MYST4 leads to a Noonan syndrome-like phenotype and hyperactivated MAPK signaling in humans and mice

  • M Kraft
  • J. Clin. Invest
  • 2011
1 Excerpt

Similar Papers

Loading similar papers…