Genomic analyses of the Chlamydia trachomatis core genome show an association between chromosomal genome, plasmid type and disease

@inproceedings{Versteeg2018GenomicAO,
  title={Genomic analyses of the Chlamydia trachomatis core genome show an association between chromosomal genome, plasmid type and disease},
  author={Bart Versteeg and Sylvia Bruisten and Yvonne Pannekoek and Keith A. Jolley and Martin C J Maiden and Arie van der Ende and Odile B Harrison},
  booktitle={BMC Genomics},
  year={2018}
}
Chlamydia trachomatis (Ct) plasmid has been shown to encode genes essential for infection. We evaluated the population structure of Ct using whole-genome sequence data (WGS). In particular, the relationship between the Ct genome, plasmid and disease was investigated. WGS data from 157 Ct isolates deposited in the Chlamydiales pubMLST database (http://pubMLST.org/chlamydiales/) were annotated with 902 genes including the core and accessory genome. Plasmid associated genes were annotated and a… CONTINUE READING
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