Genomic aberrations in hepatocellular carcinoma related to osteopontin expression detected by array-CGH


We have demonstrated that overexpression of osteopontin (OPN) could contribute to metastasis in hepatocellular carcinoma (HCC), and that OPN-positive cancer cells are often localized in the periphery of cancer nodules adjacent to stromal cells. This study was to identify the difference of intratumor genomic aberrations between OPN-positive and OPN-negative… (More)
DOI: 10.1007/s00432-009-0695-0


3 Figures and Tables