Genomic aberrations and cellular heterogeneity in SV40-immortalized human corneal epithelial cells.

@article{Yamasaki2009GenomicAA,
  title={Genomic aberrations and cellular heterogeneity in SV40-immortalized human corneal epithelial cells.},
  author={Kenta Yamasaki and Satoshi Kawasaki and Robert D Young and Hideki Fukuoka and Hidetoshi Tanioka and Mina Nakatsukasa and Andrew J Quantock and Shigeru Kinoshita},
  journal={Investigative ophthalmology & visual science},
  year={2009},
  volume={50 2},
  pages={
          604-13
        }
}
PURPOSE Simian virus (SV)40-immortalized human corneal epithelial (HCE-T) cells have been widely used as an in vitro model of human corneal epithelial cells. The nature of this cell line was assessed for genomic aberrations and cellular heterogeneity. METHODS For the quantitative measurement of genomic aberrations, array-based comparative genomic hybridization (CGH) analysis was performed. For identification of cellular heterogeneity, cell morphology, growth kinetics, transepithelial… CONTINUE READING

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