Genomic Signatures of Strain Selection and Enhancement in Bacillus atrophaeus var. globigii, a Historical Biowarfare Simulant

@inproceedings{Gibbons2011GenomicSO,
  title={Genomic Signatures of Strain Selection and Enhancement in Bacillus atrophaeus var. globigii, a Historical Biowarfare Simulant},
  author={Henry S. Gibbons and Stacey M. Broomall and Lauren A. McNew and Hajnalka Erzsebet Daligault and Carol Chapman and David Bruce and Mark A. Karavis and Michael D. Krepps and Paul A. McGregor and Charles Hong and Kyong Hwa Park and Arya Akmal and Andrew E. Feirin Jerald Feldman and Jeffrey Lin and Wenling E. Chang and Brandon W. Higgs and Plamen A. Demirev and John L. Lindquist and Alvin T. Liem and Ed T. Fochler and Timothy D. Read and Roxanne Tapia and Shannon Johnson and Kimberly A. Bishop-Lilly and Chris Detter and Cliff Han and Shanmuga Sozhamannan and C. Nicole Rosenzweig and Evan W. Skowronski},
  booktitle={PloS one},
  year={2011}
}
BACKGROUND Despite the decades-long use of Bacillus atrophaeus var. globigii (BG) as a simulant for biological warfare (BW) agents, knowledge of its genome composition is limited. Furthermore, the ability to differentiate signatures of deliberate adaptation and selection from natural variation is lacking for most bacterial agents. We characterized a lineage of BGwith a long history of use as a simulant for BW operations, focusing on classical bacteriological markers, metabolic profiling and… CONTINUE READING
15 Citations
81 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 81 references

Taxonomic Relationship of Black-Pigmented Bacillus subtilis Strains and a Proposal for Bacillus atrophaeus sp. nov

  • LK Nakamura
  • Int J Syst Bacteriol
  • 1989
Highly Influential
6 Excerpts

Similar Papers

Loading similar papers…