Genomic Features of Intertypic Recombinant Sabin Poliovirus Strains Excreted by Primary Vaccinees

@article{Cuervo2001GenomicFO,
  title={Genomic Features of Intertypic Recombinant Sabin Poliovirus Strains Excreted by Primary Vaccinees},
  author={N. Stella Cuervo and Sophie Guillot and N. I. Romanenkova and Mariana Combiescu and A. Aubert-Combiescu and Mohamed Seghier and Val{\'e}rie Caro and Radu Crainic and Francis Delpeyroux},
  journal={Journal of Virology},
  year={2001},
  volume={75},
  pages={5740 - 5751}
}
  • N. Stella Cuervo, Sophie Guillot, +6 authors Francis Delpeyroux
  • Published 2001
  • Biology, Medicine
  • Journal of Virology
  • ABSTRACT The trivalent oral poliomyelitis vaccine (OPV) contains three different poliovirus serotypes. It use therefore creates particularly favorable conditions for mixed infection of gut cells, and indeed intertypic vaccine-derived recombinants (VdRec) have been frequently found in patients with vaccine-associated paralytic poliomyelitis. Nevertheless, there have not been extensive searches for VdRec in healthy vaccinees following immunization with OPV. To determine the incidence of VdRec and… CONTINUE READING

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