Genomic Evidence for an African Expansion of Anatomically Modern Humans by a Southern Route

  title={Genomic Evidence for an African Expansion of Anatomically Modern Humans by a Southern Route},
  author={Silvia Ghirotto and Luca Penso-Dolfin and Guido Barbujani},
  booktitle={Human biology},
Abstract There is general agreement among scientists about a recent (less than 200,000 yrs ago) African origin of anatomically modern humans, whereas there is still uncertainty about whether, and to what extent, they admixed with archaic populations, which thus may have contributed to the modern populations' gene pools. Data on cranial morphology have been interpreted as suggesting that, before the main expansion from Africa through the Near East, anatomically modern humans may also have… 
Genomic and cranial phenotype data support multiple modern human dispersals from Africa and a southern route into Asia
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Early modern human dispersal from Africa: genomic evidence for multiple waves of migration
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No evidence of Neandertal admixture in the mitochondrial genomes of early European modern humans and contemporary Europeans.
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Human Pelvis and Long Bones Reveal Differential Preservation of Ancient Population History and Migration Out of Africa
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Testing Modern Human Out-of-Africa Dispersal Models Using Dental Nonmetric Data
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Why did modern human populations disperse from Africa ca. 60,000 years ago? A new model.
  • P. Mellars
  • Geography
    Proceedings of the National Academy of Sciences of the United States of America
  • 2006
It is suggested here that the answer to why it took these populations approximately 100,000 years to disperse from Africa to other regions of the world has never been clearly resolved may lie partly in the results of recent DNA studies of present-day African populations, combined with a spate of new archaeological discoveries in Africa.
Major genomic mitochondrial lineages delineate early human expansions
The relative relationships among the 42 human lineages are shown and more accurate temporal calibrations are presented than have been previously possible to give new perspectives as how modern humans spread in the Old World.
Genetic evidence of an early exit of Homo sapiens sapiens from Africa through eastern Africa
M is rendered the first genetic indicator for the hypothesized exit route from Africa through eastern Africa/western India, possibly the only successful early dispersal event of modern humans out of Africa.
Genetic evidence and the modern human origins debate
Genetic data on living human populations have been used to reconstruct the evolutionary history of the human species by considering how global patterns of human variation could be produced given different evolutionary scenarios and providing insight into the origin of modern humans.
Modern Humans Did Not Admix with Neanderthals during Their Range Expansion into Europe
A realistic model of the range expansion of early modern humans into Europe, and of their competition and potential admixture with local Neanderthals, shows that the absence of Neanderthal mtDNA sequences in Europe is compatible with at most 120 admixture events between the two populations despite a likely cohabitation time of more than 12,000 y.
Genetic evidence on the origins of Indian caste populations.
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Reconstructing Indian Population History
It is predicted that there will be an excess of recessive diseases in India, which should be possible to screen and map genetically and is higher in traditionally upper caste and Indo-European speakers.
Genetic history of an archaic hominin group from Denisova Cave in Siberia
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A Draft Sequence of the Neandertal Genome
The genomic data suggest that Neandertals mixed with modern human ancestors some 120,000 years ago, leaving traces of Ne andertal DNA in contemporary humans, suggesting that gene flow from Neand Bertals into the ancestors of non-Africans occurred before the divergence of Eurasian groups from each other.
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  • I. Tattersall
  • Biology
    Proceedings of the National Academy of Sciences
  • 2009
Modern humans appear to have definitively exited Africa to populate the rest of the globe only after both their physical and cognitive peculiarities had been acquired within that continent.