Genomic Distribution and Inter-Sample Variation of Non-CpG Methylation across Human Cell Types

Abstract

DNA methylation plays an important role in development and disease. The primary sites of DNA methylation in vertebrates are cytosines in the CpG dinucleotide context, which account for roughly three quarters of the total DNA methylation content in human and mouse cells. While the genomic distribution, inter-individual stability, and functional role of CpG… (More)
DOI: 10.1371/journal.pgen.1002389

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