Genomic Analysis of the Necrotrophic Fungal Pathogens Sclerotinia sclerotiorum and Botrytis cinerea

@article{Amselem2011GenomicAO,
  title={Genomic Analysis of the Necrotrophic Fungal Pathogens Sclerotinia sclerotiorum and Botrytis cinerea},
  author={Joelle Amselem and Christina A. Cuomo and Jan A. L. van Kan and Muriel Viaud and E. P. Benito and Arnaud Couloux and Pedro M. Coutinho and Ronald P. de Vries and Paul S. Dyer and Sabine Fillinger and Elisabeth Fournier and Lilian Gout and Matthias Hahn and Linda Myra Kohn and Nicolas Lapalu and Kim M. Plummer and J. M. Pradier and Emmanuel Quevillon and Amir Sharon and Adeline Simon and Arjen ten Have and Bettina Tudzynski and Paul Tudzynski and Patrick Wincker and Marion Andrew and V{\'e}ronique Anthouard and Ross E. Beever and Rolland Beffa and Isabelle Benoit and Ourdia Bouzid and Baptiste Brault and Zehua Chen and Mathias Choquer and J{\'e}r{\^o}me Collemare and Pascale Cotton and Etienne G. J. Danchin and Corinne Da Silva and Ang{\'e}lique Gautier and Corinne Giraud and Tatiana Giraud and Celedonio Gonz{\'a}lez and Sandrine Grosset{\^e}te and Ulrich G{\"u}ldener and Bernard Henrissat and Barbara J. Howlett and Chinnappa D. Kodira and Matthias Kretschmer and Anne C. Lappartient and Michaela Leroch and Carolina Levis and Evan Mauceli and C{\'e}cile Neuv{\'e}glise and Birgitt Oeser and Matthew D. Pearson and Julie Poulain and Nathalie Poussereau and Hadi Quesneville and Christine Rascle and Julia Schumacher and B{\'e}atrice S{\'e}gurens and Adrienne Sexton and Evelyn Silva and Catherine Sirven and Darren M. Soanes and Nicholas J. Talbot and Matthew D. Templeton and Chandri N. Yandava and Oded Yarden and Qiandong Zeng and Jeffrey A. Rollins and Marc-Henri Lebrun and Martin Dickman},
  journal={PLoS Genetics},
  year={2011},
  volume={7}
}
Sclerotinia sclerotiorum and Botrytis cinerea are closely related necrotrophic plant pathogenic fungi notable for their wide host ranges and environmental persistence. These attributes have made these species models for understanding the complexity of necrotrophic, broad host-range pathogenicity. Despite their similarities, the two species differ in mating behaviour and the ability to produce asexual spores. We have sequenced the genomes of one strain of S. sclerotiorum and two strains of B… 
Genomics of Sclerotinia sclerotiorum
TLDR
An overview of the notable aspects of the genome structure, life cycle, and basis of pathogenesis is provided, and future challenges and opportunities for applying this genome data as a resource for managing disease and understanding the evolution of necrotrophic pathogenicity are discussed.
Genome sequence of the necrotrophic fungus Penicillium digitatum, the main postharvest pathogen of citrus
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The complete genome of P. digitatum, the first of a phytopathogenic Penicillium species, is a valuable tool for understanding the virulence mechanisms and host-specificity of this economically important pest.
The host generalist phytopathogenic fungus Sclerotinia sclerotiorum differentially expresses multiple metabolic enzymes on two different plant hosts
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Results suggest that S. sclerotiorum may regulate the expression of detoxification-related genes in response to phytotoxins produced by the different host species, suggesting involvement in the broader infection process.
An Interspecies Comparative Analysis of the Predicted Secretomes of the Necrotrophic Plant Pathogens Sclerotinia sclerotiorum and Botrytis cinerea
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Detailed in silico analyses of two important necrotrophic pathogens will permit informed choices to be made when candidate effector proteins are selected for function analyses in planta.
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High-quality sequences from two strains of B. cinerea revealed an average-sized genome with a low fraction of repetitive DNA and no specific features correlated with its pathogenic lifestyle, except for a large number of genes encoding pectin-degrading enzymes that are particularly active on cell walls of dicot hosts.
Interkingdom Gene Transfer May Contribute to the Evolution of Phytopathogenicity in Botrytis Cinerea
TLDR
A correlation between gene acquision and the evolution of pathogenicity in B. cinerea can be postulated after a stringent genome comparison pipeline was used to identify potential genes that have been obtained by the fungus but not by other fungi through interkingdom HGT.
The Complete Genome Sequence of the Phytopathogenic Fungus Sclerotinia sclerotiorum Reveals Insights into the Genome Architecture of Broad Host Range Pathogens
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It is concluded that S. sclerotiorum exhibits subtle signatures of enhanced mutation of secreted proteins in specific genomic compartments as a result of transposition and RIP activity, however, these signatures are not observable at the whole-genome scale.
Prediction of pathogenicity genes involved in adaptation to a lupin host in the fungal pathogens Botrytis cinerea and Sclerotinia sclerotiorum via comparative genomics
TLDR
Detection of minor differences between relatively recently-diverged isolates, originating from distinct regions and with hosts, may highlight novel or recent gene mutations and losses resulting from host adaptation in broad host-range fungal pathogens.
Comparative Transcriptome Analysis between the Fungal Plant Pathogens Sclerotinia sclerotiorum and S. trifoliorum Using RNA Sequencing.
TLDR
Comparisons of transcriptomes of the 2 species at vegetative growth stage discovered similarities and uniqueness in gene expression between the 2 closely related species, providing additional information for annotation the S. sclerotiorum genome and provided foundation for comparing the transcriptomes with host-infecting transcriptomes.
Emerging Trends in Molecular Interactions between Plants and the Broad Host Range Fungal Pathogens Botrytis cinerea and Sclerotinia sclerotiorum
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This minireview highlights a selection of nine themes that emerged in recent research reports on the molecular bases of plant-S.
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