Genomewide identification of genetic determinants of antimicrobial drug resistance in Pseudomonas aeruginosa.

@article{Doetsch2009GenomewideIO,
  title={Genomewide identification of genetic determinants of antimicrobial drug resistance in Pseudomonas aeruginosa.},
  author={Andreas Doetsch and Tanja Becker and Claudia Pommerenke and Zofia Magnowska and Lothar J{\"a}nsch and S. H{\"a}u\ssler},
  journal={Antimicrobial agents and chemotherapy},
  year={2009},
  volume={53 6},
  pages={2522-31}
}
The emergence of antimicrobial drug resistance is of enormous public concern due to the increased risk of delayed treatment of infections, the increased length of hospital stays, the substantial increase in the cost of care, and the high risk of fatal outcomes. A prerequisite for the development of effective therapy alternatives is a detailed understanding of the diversity of bacterial mechanisms that underlie drug resistance, especially for problematic gram-negative bacteria such as… CONTINUE READING