Genomewide association studies: history, rationale, and prospects for psychiatric disorders.

@article{Cichon2009GenomewideAS,
  title={Genomewide association studies: history, rationale, and prospects for psychiatric disorders.},
  author={Sven Cichon and Nick J. Craddock and Mark Daly and Stephen V Faraone and Pablo V. Gejman and John Kelsoe and Thomas Lehner and Douglas F. Levinson and Audra Moran and Pamela Sklar and Patrick F. Sullivan},
  journal={The American journal of psychiatry},
  year={2009},
  volume={166 5},
  pages={540-56}
}
OBJECTIVE The authors conducted a review of the history and empirical basis of genomewide association studies (GWAS), the rationale for GWAS of psychiatric disorders, results to date, limitations, and plans for GWAS meta-analyses. METHOD A literature review was carried out, power and other issues discussed, and planned studies assessed. RESULTS Most of the genomic DNA sequence differences between any two people are common (frequency >5%) single nucleotide polymorphisms (SNPs). Because of… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 89 references

The International HapMap Project

Nature • 2003
View 3 Excerpts
Highly Influenced

GENOMEWIDE ASSOCIATION STUDIES ajp.psychiatryonline.org

RJ Loos, CM Lindgren, +45 authors Il
Am J Psychiatry • 2009

PSYCHIATRIC GWAS CONSORTIUM COORDINATING COMMITTEE ajp.psychiatryonline.org

MB McQueen, B Devlin, +25 authors JR Kelsoe
Am J Psychiatry • 2009

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