Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.

@article{Kendler2011GenomewideAA,
  title={Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.},
  author={Kenneth S. Kendler and Gursharan Kalsi and Peter Holmans and Alan R. Sanders and Steven H. Aggen and Danielle M Dick and Fazil Aliev and Jianxin Shi and Douglas F. Levinson and Pablo V. Gejman},
  journal={Alcoholism, clinical and experimental research},
  year={2011},
  volume={35 5},
  pages={963-75}
}
BACKGROUND While genetic influences on alcohol dependence (AD) are substantial, progress in the identification of individual genetic variants that impact on risk has been difficult. METHODS We performed a genome-wide association study on 3,169 alcohol consuming subjects from the population-based Molecular Genetics of Schizophrenia (MGS2) control sample. Subjects were asked 7 questions about symptoms of AD which were analyzed by confirmatory factor analysis. Genotyping was performed using the… CONTINUE READING

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