• DOI:10.1097/01.tp.0000250485.53865.b8
Corpus ID: 22022837

Genomewide Expression Profiles of Rat Model Renal Isografts From Brain Dead Donors

@article{Kusaka2007GenomewideEP,
  title={Genomewide Expression Profiles of Rat Model Renal Isografts From Brain Dead Donors},
  author={M. Kusaka and Y. Kuroyanagi and H. Kowa and K. Nagaoka and T. Mori and K. Yamada and R. Shiroki and H. Kurahashi and K. Hoshinaga},
  journal={Transplantation},
  year={2007},
  volume={83},
  pages={62-70}
}

M. Kusaka, Y. Kuroyanagi, +6 authors K. Hoshinaga

Published 2007

Medicine

Transplantation

Background. It has been well documented that two factors, brain death (BD) and ischemia/reperfusion (I/R) injury, have distinct but overlapping adverse influences on the clinical outcome of renal transplantation. Method. We previously established a rat model of renal isografting from brain dead donors. In the present study, we performed genomic expression profiling with a high-density oligonucleotide microarray to identify genes that were upregulated or downregulated by BD and/or I/R injury… CONTINUE READING

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