Genomes of trombidid mites reveal novel predicted allergens and laterally transferred genes associated with secondary metabolism

  title={Genomes of trombidid mites reveal novel predicted allergens and laterally transferred genes associated with secondary metabolism},
  author={Xiaofeng Dong and Kittipong Chaisiri and Dong Xia and Stuart Armstrong and Yongxiang Fang and Martin James Donnelly and Tatsuhiko Kadowaki and John Mcgarry and Alistair C. Darby and Benjamin L. Makepeace},
Abstract Background Trombidid mites have a unique life cycle in which only the larval stage is ectoparasitic. In the superfamily Trombiculoidea (“chiggers”), the larvae feed preferentially on vertebrates, including humans. Species in the genus Leptotrombidium are vectors of a potentially fatal bacterial infection, scrub typhus, that affects 1 million people annually. Moreover, chiggers can cause pruritic dermatitis (trombiculiasis) in humans and domesticated animals. In the Trombidioidea… 
Molecular evolutionary trends and biosynthesis pathways in the Oribatida revealed by the genome of Archegozetes longisetosus
A 190-Mb genome assembly of the clonal, all-female oribatid mite species Archegozetes longisetosus Aoki is presented, a model species used by numerous laboratories for the past 30 years to serve as the foundation for molecular research in Oribatida and enable a broader understanding of chelicerate evolution.
Targeted capture and sequencing of Orientia tsutsugamushi genomes from chiggers and humans
  • I. Elliott, N. Thangnimitchok, E. Batty
  • Biology
    Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
  • 2021
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In this mini-review, the current situation of mite and tick genomes were described and the future perspectives for the application of the genomic resources are discussed, in particular the identification and structural analysis of allergens.
Small genomes in most mites (but not ticks)
A notable distinction in genome size between the comparatively larger genomes of ticks versus the (sometimes extremely) small genomes of non-tick mites is reported.


Genomes of trombidid mites reveal novel predicted allergens and laterally-transferred genes associated with secondary metabolism
The first trombidid mite genomes are presented, obtained both for a chigger, Leptotrombidium deliense, and for a velvet mite, Dinothrombium tinctorium, and both exhibited evidence of ancient lateral gene transfer from soil-derived bacteria or fungi.
Detection of a Novel Rickettsia From Leptotrombidium scutellare Mites (Acari: Trombiculidae) From Shandong of China
A unique Rickettsia species was detected in L. scutellare chiggers, which expanded the knowledge on the vector distribution of Rickettsias, and was named CandidatusRickettsia leptotrombidium.
A massive incorporation of microbial genes into the genome of Tetranychus urticae, a polyphagous arthropod herbivore
HGT has made a significant and underestimated impact on the metabolic repertoire of plant‐feeding spider mites, and the evolutionary histories of these HGTs during chelicerate evolution are estimated.
Draft genome of the scabies mite
The identification of antigen-producing genes, candidate immune modulating proteins and pathways, and genes responsible for acaricide resistance offers opportunities for developing new methods for diagnosing, treating and preventing this disease.
Draft genome of the honey bee ectoparasitic mite, Tropilaelaps mercedesae, is shaped by the parasitic life history
Comparison of the genome and transcriptome sequences of Tropilaelaps mercedesae, the prevalent ectoparasitic mite infesting honey bees in Asia, and Varroa destructor, not only provide insights into the mite biology, but may also help to develop measures to control the most serious pests of the honey bee.
Genomic insights into the Ixodes scapularis tick vector of Lyme disease
Insights from genome analyses into parasitic processes unique to ticks, including host ‘questing', prolonged feeding, cuticle synthesis, blood meal concentration, novel methods of haemoglobin digestion, haem detoxification, vitellogenesis and prolonged off-host survival are reported.
The Rickettsia Endosymbiont of Ixodes pacificus Contains All the Genes of De Novo Folate Biosynthesis
It is shown that all folate genes exist in the genome of Rickettsia species phylotype G021 and that this bacterium has the genetic capability for de novo folate synthesis.
Comparative Analysis of the Secretome from a Model Filarial Nematode (Litomosoides sigmodontis) Reveals Maximal Diversity in Gravid Female Parasites*
Comparison of the L. sigmodontis adult secretome with that of the human-infective filarial nematode Brugia malayi identified differences that suggest a considerable underlying diversity of potential immunomodulators, showing promise not only for vaccination against filarial infections, but for the amelioration of allergy and autoimmune diseases.
The Salivary Protein Repertoire of the Polyphagous Spider Mite Tetranychus urticae: A Quest for Effectors*
A meta-analysis of the proteomic composition of saliva from T. urticae lines adapted to various host plants revealed for the first time the salivary protein repertoire of a phytophagous chelicerate, which will assist in unraveling the molecular interface between phytophileous mites and their host plants and may ultimately facilitate the development of mite-resistant crops.
Genome Sequencing of the Phytoseiid Predatory Mite Metaseiulus occidentalis Reveals Completely Atomized Hox Genes and Superdynamic Intron Evolution
The genome of the western orchard predatory mite improves genomic sampling of chelicerates and provides invaluable new resources for functional genomic analyses of this family of agriculturally important mites.